Top Most Addictive Illegal Drugs

Top Most Addictive Illegal Drugs

Do you know how the drug that is addictive is you are currently taking? While many factors determine whether or not you will become hooked on drugs, the risks related to becoming addicted to your drugs is greater than others. The reason? While others may take to get addicted to — a few drugs may have you hooked after just the first try — drugs have varying degrees of addictiveness.


Heroin’s capacity to swiftly penetrate the mind results in the surge of intense euphoria or the “rush” heroin addicts encounter.

Additionally, heroin activates your brain’s reward system. It tricks the brain into halting the production of reward feelings so that the consumer can experience no feelings without the assistance of the drug. This is why heroin users experience drug cravings when the drug is stopped.

Top this with severe withdrawal symptoms, and you’ve got the world’s most addictive substance.

Crack Cocaine:

Hunting as stones, it is heated and smoked through a glass hand pipe.

Like heroin, crack cocaine also activates the reward system and causes excessive amounts of dopamine, the neurotransmitter from the benefit circuit responsible for feelings of pleasure, to be released.

Smoking crack allows it to reach the brain faster than if it were snorted, resulting in an intense and immediate high that lasts around 15 minutes. Since the effects are so short lived, users frequently smoke it to maintain. It is not unusual for someone to become hooked after their first time.


Just because smoking is legal does not mean we should transcend the addictive effects of nicotine. According to the National Institute on Drug Abuse, nearly 35 million smokers want to quit annually, but over 85 percent of people who attempt to quit on their relapse– many per week.

Half of this addictive nature of nicotine come from nicotine’s ability to activate the reward pathway by increasing amounts of dopamine. Nicotine mimics another compound in mind–the receptors. Normal smoking requires the user maintain ingesting nicotine to maintain normal brain functioning and lowers the number and sensitivity of these receptors.


Methadone is an opiate medication commonly utilized to deal with heroin or morphine dependence, so at a clinical setting, tolerance to this drug is deemed beneficial. While the risk for addiction is low (less than one %) when taken as prescribed and under medical supervision, people using this medicine recreationally can become hooked. Methadone’s effects are very similar to the consequences of heroin, but withdrawal from methadone is painful and arduous, often lasting more than a month.


Methamphetamine imitates none but two major compounds in the brain: dopamine and norepinephrine, the neurotransmitter responsible for feelings of alertness and energy (adrenaline).

Meth can discharge as much as ten times the standard level of dopamine, and also the excess of artificial norepinephrine inhibits organic adrenaline production–mainly messing up the chemical balance in the brain. Worse, methamphetamine can harm the dopamine and neurons, causing a drop in their output.

You guessed it. Tolerance, cravings, and taking meth.


Alcohol influences two Major chemicals in the brain that triggers addiction:

Dopamine: Like the others, alcohol triggers the reward system and produces feelings of satisfaction and pleasure.

Endorphins: Endorphins are the brain’s natural painkiller, and recent research is revealing how increased levels of endorphins may increase the pleasurable effects of alcohol, especially in heavy drinkers.

Alcohol withdrawal can also be among the worst of all drug withdrawals, so acute it could cause death.


Cocaine may not have the same withdrawal symptoms seen in alcohol dependence, but cocaine functions in precisely the same way: it contrasts with the amount of dopamine in the brain and causes intense cravings. Snorting cocaine is much behind although smoking crack is the quickest way to get cocaine into your blood vessels. Powder cocaine has a short rapid and high tolerance.


Though amphetamines aren’t as addictive as meth, it still acts on precisely the same reward circuit. Amphetamines give an array of effects: weight loss, assurance, euphoria, energy, and feelings of self-accomplishment besides inducing rapid endurance and extreme cravings. Abusers of Adderall and Ritalin find it hard to stop, but they don’t even wish to leave.


Benzodiazepines such as Valium, Xanax, and Klonopin increases the effectiveness of GABA, the brain’s “nerve calming” agent. (For once, we’re not talking about dopamine!) And, like usual, the body attempts to compensate for the increase of GABA by lowering the sensitivity of GABA receptor tissues. As the body continues to accommodate, tolerance builds fast and quitting gets harder when tolerance is high.

How Drugs Mess with Dopamine:

Dopamine is the medication that produces the feeling of gratification and well-being. By attaching to dopamine receptors, dopamine enters neurons. When levels of dopamine increases, your body attempts to balance out the extra dopamine. Therefore, when an individual stops taking the drug, dopamine levels drop drastically, which is the drug is craved by the individual so much. After all, your body needs its dopamine.

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